Leptin Resistance: The Real Reason You Can’t Lose Weight
Posted on 26. Mar, 2009 by Core Health Expert in Leptin and Weight Loss
Is it difficult to suppress tears when you look in the mirror? Do you shun shopping for new clothes because you can’t bear the thought of needing a larger size than last year? Are you sick and tired of your thyroid medication not doing its job?
Male or female, we all want to look our best and feel healthy. A woman’s weight is closely tied with her self-image. She’s been trained by the media and society to be pretty, nice, and thin. And when she’s not thin or at her ideal weight, it’s more difficult to be pretty in her own mind.
You’ve been waiting for years for science to solve the obesity problem. You’ve had enough of diets that don’t work and gave up hope you can eat anything since every calorie seems to multiply itself by a factor of 5. And you’ve had it with food cravings that keep your mind focused on food all day long.
Why has your body turned against you? Where is your answer?
With all the thousands of research studies published each year, isn’t it possible that there is an answer somewhere? Maybe…
Newly Discovered Hormone Affects Your Weight
The hormone leptin itself was just recently discovered. When it was, it was viewed as the ‘new frontier’ of weight loss. Why? Well, it may have something to do with the fact that two of its most influential effects are on controlling cravings and burning body fat. But as the science advanced we learned that due to a number of factors, mainly overeating and eating too much of the wrongs foods, people who were chronically over weight and obese were resistant to leptin’s powerful effects. That reason is now known as “Leptin Resistance.”
The truth is that leptin is exceptionally crucial to your body to function optimally. The hormone has a hand in controlling the two most important factors in weight control; food intake and fat storage. But also sexual development, immunity, GI function, reproduction, the nervous system during stressful times, brain function and red blood cell production.
“Leptin Resistance” is extremely similar in nature to “Insulin Resistance” and although most people are completely unaware that they even have this hormonal dysfunction, it is extremely common. “Leptin Resistance” occurs when the body is no longer efficient at carrying Leptin across the blood-brain barrier to the brain, specifically the hypothalamus. In order for Leptin to perform it’s ‘weight loss magic’ to control your body weight and metabolism, it has to do so from the hypothalamic centers in the brain. When brain levels of Leptin are low because the brain never ‘hears’ or ‘receives’ it due to “Leptin Resistance” - food cravings and weight gain occur because the body believes that it is hungry and will daily go into a state of persistent fat storage.
“NORMAL BRAIN LEVELS OF LEPTIN ARE ABSOLUTELY VITAL IF YOU WANT TO CONTROL YOUR BODY WEIGHT AND METABOLISM”
The Research Proves It
By restoring leptin sensitivity, weight may come off like never before and food cravings can be subdued. You may can lose weight safely, and that’s not all: thyroid function can improve.
In a study reported in the New England Journal of Medicine in February of 2009, when calories were restricted 40% for 25 days, significantly reduced leptin, thyroid hormones and increased corticosteroid levels resulted. Leptin replacement for the last 10 days of the study normalized the leptin and TSH levels.
In a University of Miami study reported in August 2008, leptin replacement in a 5-year-old morbidly obese boy with leptin gene mutation resulted in substantial increases in the rates of brain development with some skills increasing more than what was expected for his age. High blood pressure reversed totally as did high levels of insulin and fat abnormalities.
In another case study, a female with type 2 diabetes treated with leptin replacement decreased her insulin resistance and lost weight.
Scientists have found that overweight individuals can have leptin resistance. In fact, researchers at Harvard, in the journal Developmental Cell, say that “Almost all forms of obesity are leptin-resistant ….” Leptin resistance is similar to insulin resistance and results in health problems that can contribute to diabetes and lead to diabetes medication.
If you have been chronically over weight or obese, chances are there has been a strong reason why you haven’t been able to lose weight. Most likely, you are suffering from leptin resistance. Let’s chalk one up for science here, as this is a BIG discovery. People are now searching for ‘leptin supplements.’
What you need to do is increase your leptin signaling pathway. There is only one supplement I know of that does this, LepToThin™. When you improve leptin signaling, it’s truly natural weight loss.



One Comment
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28. Mar, 2009
[...] In general high levels of serum insulin promote eating (food cravings) and fat storage. Insulin should be at it lowest when you wake. So [...]
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