From the category archives:

Leptin and Weight Loss

ScienceFairThe best of the newest weight loss science at a fourth grade level.

A significant amount of the newest science and research attempting to tackle America’s growing obesity problem is focused on hormonal disruptions and imbalances such as leptin resistance. LepToThin™ is natural science’s newest answer, in supplement form, to help address this issue. LepToThin™ contains LeptiPro™ which is the primary active ingredient to assist in improving leptin signaling. The main mechanism of action of this supplement occurs by inhibiting protein tyrosine phosphatase 1B, commonly known as (PTP1B). A plethora of research is currently being performed to assess the efficacy of PTP1B in the treatment of obesity, insulin resistance and leptin resistance.

To help your understanding of this ever-important concept and physiological cascade of events, I’ll provide a number of credible research excerpts followed by my ‘fourth grade version’ and interpretation. This should help you get to the bottom line on how and why this can significantly help you in your quest to lose weight naturally and improve your health.

Deal? Here we go… [click to continue reading…]

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If you’ve read my blog before, you probably know that it’s not only my opinion but ever mounting research, that leads me to proclaim that one of the most important, yet most overlooked factors in losing weight is dependent upon the body’s ability to respond properly to the hormones that are largely responsible for maintaining your weight. The newest science shows that leptin resistance is the hallmark of obesity induced by a high-fat diet in rodents, and occurs naturally in obese humans. How do we put a stop to diet induced obesity?

Let’s talk about leptin and insulin…

The ensuing results that occur when attending to and normalizing the function of these two hormones can be accurately described as losing weight naturally. Leptin and insulin are two master hormones when it comes to controlling weight and body composition. When they’re allowed to work, weight management is a self-regulating system. In a recent study, very overweight mice actually doubled their amount of physical activity when the hormone leptin – which regulates appetite and energy expenditure (fat burning)- was switched on in their brain. In fact, when leptin signaling was ‘turned on’ in the brain, the study quotes, “remarkably, blood glucose levels are entirely normalized.”

Totally normalizing blood sugar? Doubling the amount of exercise one is capable of? It’s time the public was let in on this.

Diet induced, type 2 diabetes has risen in this country to levels never seen before.

It’s even infiltrated the future of the nation-our youth.

diet-induced-type-2-diabetes

Insulin resistance…leptin resistance…. what to do? Who’s the chicken? Who’s the egg?

If the culprit of this ever growing obesity and overweight problem was a popularity contest, insulin resistance would win by a mile.

But some research is pointing to the fact that leptin resistance may be an underlying precursor to insulin resistance. We need to rethink weight loss in lieu of these observations. Of note, leptin can also be found in skeletal muscle. The increased risk of diabetes that comes with obesity ay be caused in part by increased lipid deposits in that skeletal muscle as well as the liver, creating insulin resistance. Here is a wonderful illustration showing the reversal of insulin resistance by leptin.

A new study In the  June 2009 issue of the medical journal Cell Metabolism,  shows the astounding possibilities of what can happen once leptin resistance is restored. Raise your hand if your overweight but just don’t have the energy to exercise. OK, more than a few hands went up. Now…read carefully… [click to continue reading…]

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leptin_resistance_thyroidContrary to popular belief, there are plenty of people who try to exercise and eat right and still can’t lose weight.

Though most recent literature continues to show that the majority of overweight people suffer from a condition called ‘leptin resistance,’ it’s still unknown to the majority who suffer from it,  yet it’s the very hurdle that thwarts bold efforts to lose weight.

More research has turned up exposing leptin resistance and reverse T3 (a thyroid hormone which can lower your metabolism) as primary factors in the battle to lose weight and as big factors in the CAUSE of excessive weight gain.

Leptin resistance can contribute to reverse T3 production and that undermines your thyroids attempt at regulating your metabolism. When these metabolic self-regulating systems are upset, it makes it nearly impossible to lose weight and highly probable that you’ll gain weight, despite your efforts- rendering will power virtually useless.

There’s a lot to be said for the adage which promises that if you take in less calories than you burn, you will lose weight. I would agree that statement holds true for most anyone that has a normally functioning, healthy body.

But the issue  that seems to be eluding even the most learned of advisers and dieters when attempting to be successful at weight loss is this… people who are overweight just don’t have normally functioning healthy bodies.

In fact, in my experience, most all patients I’ve dealt with who are chronically overweight, have an endocrine or metabolic syndrome or dysfunction. And unfortunately it can sabotage and diminish the effects of exercise and eating right.

Dr. Kent Holtorf, medical director at Holtorf Medical Group, says that weight gain and the inability to lose weight “is not simply a problem that individuals are taking in more calories … or lack of exercise or willpower.”

Meaning that there may be more to it than the simple “calories in” vs. “calories out” theory.

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Brain Surgery for Weight Loss? Oprah, Please Read This…

by Core Health Expert

Brain surgery for weight loss? There must be an alternative.
Doh…Thank God, there is.
On Oprah’s most recent show, Dr. Oz explains a new experimental weight loss surgery that basically consists of cutting holes in the skull and then inserting probes into the brain, to control the area of the brain responsible for hunger and cravings. Next, [...]

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LeptiPro™: What Is It and Why Is It So Powerful As a Weight Loss Supplement?

by Core Health Expert

There is mounting evidence that the clinical efficacy of purified API-grade Berberine shows potent and specific inhibition of PTP1B, among other important mechanisms dealing with weight loss, weight control, and the hormones that influence those functions.

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